The clinical trial results were impressive: CurcuWIN increased serum curcuminoid levels at least 46 times over standard curcumin. Importantly, instead of comparing against standard curcumin ingredients, which may not be very bioavailable, the researchers also made sure to compare CurcuWIN to other bioavailable curcumin ingredients for comparable results. CurcuWIN was more bioavailable by far. University of Tampa and Increnovo.Jäger et al. Nutritional Journal 2014 13:11. Discussion of Relentless Improvement's CurcuWin Curcumin product vs Longvida Curcumin product: Longvida used "fat-fed" test subjects (cream cheese bagels) which greatly influenced the test results to their benefit (3x-4x). Longvida study was not peer-reviewed. Jaeger CurcuWin study was conducted on fasting subjects, a "worst-case" scenario for curcumin bioavailability. Fat-fed vs fasting subject bioavailability and duration of plasma levels is approximately 3-4x difference! The Jaeger study dose was 376mg of CurcuWin vs the Longvida study used a 650mg dose (almost twice as much) In spite of all the factors in Longvida's favor, the Longvida still takes more than twice as long to reach its (lower) peak and falls off precipitously while CurcuWin maintains very high plasma levels. Longvida material is very similar to Meriva product in its chemical composition. PK studies of the two could therefore be reasonably inferred to be essentially identical in result. CurcuWin's unique formulation inhibits formations of conjugates, bad metabolites of curcumin, and promotes good metabolites such as THC- TetrahydroCurcuminoids.
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